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Inhibitors of Bile Salt Efflux Pump: Stay clear of concomitant utilization of inhibitors from the bile salt efflux pump (BSEP) for example cyclosporine. Concomitant drugs that inhibit canalicular membrane bile acid transporters such as the BSEP may well exacerbate accumulation of conjugated bile salts including taurine conjugate of obeticholic aci